Meningiomas May Be a Component Tumor of Multiple Endocrine Neoplasia Type 1
نویسندگان
چکیده
منابع مشابه
Meningiomas may be a component tumor of multiple endocrine neoplasia type 1.
PURPOSE Recently, an increased incidence of some nonendocrine tumors are reported in patients with multiple endocrine neoplasia type 1 (MEN 1). There are rare reports of meningiomas and other central nervous system tumors in these patients, but it is unknown if they are more frequent or if allelic loss of the MEN1 gene is important in their pathogenesis. The aim of this study was to address the...
متن کاملMultiple endocrine neoplasia type 1
Combined clinical and laboratory investigations of MEN-1 have resulted in an increased understanding of this disorder, which may be inherited as an autosomal dominant condition. Defining the features of each disease manifestation in MEN-1 has improved patient management and treatment and has facilitated a screening protocol. Application of the techniques of molecular biology has enabled the ide...
متن کاملMultiple endocrine neoplasia type 1.
Multiple endocrine neoplasia-1 (MEN-1) is an autosomal dominant inherited syndrome that occurs due to inactivating mutations of the MEN1 gene locus, coding for a tumor-suppressor protein, menin. The components of MEN-1 are hyperparathyroidism due to multiple parathyroid adenomas, pancreatic neuroendocrine tumors, and pituitary adenomas, in addition to some less common neoplastic manifestations....
متن کامل[Astrocytoma in a patient with multiple endocrine neoplasia type 2A syndrome. May the coexistence of glial tumors and multiple endocrine neoplasia 2A not be casual?].
5. Rayner CK, Samsom M, Jones KL, Horowitz M. Relationship of upper gastrointestinal motor and sensory function with glycemic control. Diabetes Care. 2001;24:371. 6. Hummel M, Geigenberger G, Brand J, Ziegler AG, Füchtenbusch M. New therapeutic approaches to diabetic gastroparesis. Med Klin (Munich). 2008;103:514--8. 7. Van Heel DA, Levitt NS, Winter TA. Diabetic neuropathic cachexia: the impor...
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ژورنال
عنوان ژورنال: Clinical Cancer Research
سال: 2004
ISSN: 1078-0432,1557-3265
DOI: 10.1158/1078-0432.ccr-0938-3